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Hefei Evergreen Chemical Industry Co., Ltd.

Sirolimus, 53123-88-9, Rapamycin manufacturer / supplier in China, offering 99.0% Pharmaceutical Raw Materials Sirolimus (CAS 53123-88-9), Bicalutamide with High Quality From Chinaese Supplier CAS 90357-06-5, Oxygen-Fluorine Acid (CAS 82419-35-0) From China Factory and so on.

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Supplier Homepage Product Pharmaceutical Chemicals 99.0% Pharmaceutical Raw Materials Sirolimus (CAS 53123-88-9)

99.0% Pharmaceutical Raw Materials Sirolimus (CAS 53123-88-9)

FOB Price: Get Latest Price
Min. Order: 1 G
Port: Shanghai, China
Transport Package: 1g/Aluminum Bag
Payment Terms: L/C, T/T, Western Union

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Basic Info
  • Model NO.: 53123-88-9
  • Customized: Non-Customized
  • Suitable for: Elderly, Children, Adult
  • Purity: >99%
  • Specification: 1g/bag. Enterprise standard 99.0%
  • HS Code: 29420000
  • Powder: Yes
  • Certification: Enterprise Standard
  • State: Solid
  • Trademark: EVERGREEN
  • Origin: Anhui China
Product Description
Product name:Sirolimus
Chemical name:23,27-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
CAS No.:53123-88-9
Molecular Formula:C51H79NO13
Formula Weight:914.17
Structural formula:
       99.0% Pharmaceutical Raw Materials Sirolimus (CAS 53123-88-9)
Properties:
Appearance: White or off-white crystalline powder. Dissolved in methanol, ethanol, acetone and other organic solvents, soluble in water, insoluble in ether.
Density:1.182 g/cm³
melting point:183-185ºC
Boiling Point:973.017ºC at 760 mmHg
Flash Point:542.261ºC

Quality Specification:
Enterprise standard, ≥99.5%  

 
ItemStandardResult
AppearanceAn odorless, white to off-white crystalline powderComplies
Identification
1.Exhibit maxima at 267nm, 277nm, and 288nmComplies
2.The retention times of the peaks for the cis-and trans-stereoisomers in the chromatogram of the assay preparation corresponds to those of the standard preparation as obtained in the assay respectively.Complies
3.The infrared absorption spectrum is concordant with the  spectrum of sirolimus reference standardComplies
Chromatographic Purity
Individual ImpurityNot more than 1.0%0.25%
Total ImpurityNot more than 2.0%0.30%
Cis-Stereoisomer of SirolimusNot more than 5.0%1.9%
WaterNot more than 0.5%0.03%
Heavy metalNot more than 20ppmComplies
Assay98.0%-102% (calculated cis-and trans-stereisomers of sirolimus on the anhydrous basis)100.0%
Conclusion:Up to standard for export
 
Application:
It has immunosuppressant functions in humans and is used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It prevents activation of T cells and B cells by inhibiting their response to interleukin-2 (IL-2). Sirolimus is also used as a coronary stent coating. Sirolimus works, in part, by eliminating old and abnormal white blood cells.[citation needed] Sirolimus is effective in mice with autoimmunity and in children with a rare condition called autoimmune lymphoproliferative syndrome (ALPS).
Biological activity,antifungal and immunosuppressant.

Packaging:
1g/Aluminum bag.

 
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